Experimental

There are nearly 60 years has been shown that injecting brain extracts from animals, in some cases cause an inflammatory disease of the central nervous system (CNS) and experimental allergic encephalitis (EAE). EAE is very similar to the human disease caused by the administration of the preparation containing fragments rabies vaccine ancient myelin. This form of encephalitis, in turn, is very similar to the pathology observed some forms of encephalomyelitis after infectious sometimes in children after a viral infection (measles, rubella, chicken pox, or otherwise). After infectious encephalomyelitis recurrent disease in humans.

Shortly thereafter, it was shown that it can cause chronic form of relapsing EAE in animals genetically engineered to have ready a few weeks or months and then after the initial recovery episode of paralysis, and the animals showed symptoms similar to those of the new MS. In addition, it was observed signs of harm in the central nervous system of these animals, similar to that of MS.