Sunday, September 23, 2012

Experimental


There are nearly 60 years has been shown that injecting brain extracts from animals, in some cases cause an inflammatory disease of the central nervous system (CNS) and experimental allergic encephalitis (EAE). EAE is very similar to the human disease caused by the administration of the preparation containing fragments rabies vaccine ancient myelin. This form of encephalitis, in turn, is very similar to the pathology observed some forms of encephalomyelitis after infectious sometimes in children after a viral infection (measles, rubella, chicken pox, or otherwise). After infectious encephalomyelitis recurrent disease in humans.

Shortly thereafter, it was shown that it can cause chronic form of relapsing EAE in animals genetically engineered to have ready a few weeks or months and then after the initial recovery episode of paralysis, and the animals showed symptoms similar to those of the new MS. In addition, it was observed signs of harm in the central nervous system of these animals, similar to that of MS.

Better Understand The Disease

To better understand the disease better treatment

Although he does not know with certainty that the cause of MS is probably immune mediated process of environmental factors (perhaps viral infections) caused in genetically predisposed individuals. May be determined susceptibility for MS by multiple genes.

Current theories in favor of immune etiology of MS, it is not necessary little reminder theoretically. The immune system is to detect and destroy bacteria, viruses and other exotic materials (antigens). To do so, we must be able to distinguish any part of the anti-body, which is foreign to external influences. However, in certain medical conditions (autoimmune disease), the immune system no longer recognizes self components and MS attack, there is every reason to believe that the immune system attack the myelin occurs, a substance that form insulating sheath around the nerve fibers of many.

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