Sunday, September 22, 2013

Cancer chemotherapy


An updated work has been known bleaching of gasoline for many years due to the increased frequency of LA in chronic occupational exposure .

Is documented well the role of ionizing radiation , both in atomic bomb survivors than in patients who are exposed professionally. Similarly, patients with radiation therapy or isotope products treated at an increased risk for AML , and then classified as a so - called anti-money laundering and secondary .

For more than 20 years, and we also know that cancer chemotherapy by types of acute leukemia secondary AML can be complicated . There are two main types of anti-money laundering and secondary . (Table 2) is to combat money laundering and classic . Following the use of alkylating agents as described after treatment for Hodgkin's disease when they are associated with the type of treatment ( MOP ) and a number of applications. They are characterized by a delay in the emergence of 5-7 years , the incidence of dysplasia stage introductions myelogenous leukemia often indiscriminate nature and association with cytogenetic abnormalities of chromosomes 5 and / or 7 they are often chemoresistant and poor prognosis . Recently , it was reported prevents secondary AML with modes topoisomerase II : epipodophylotoxines (VP16 and VM 26 ) and Antrasiklin. This is described in the majority of solid tumors after treatment. They are characterized by the shorter time for the beginning ( 2-3 years) , similar to those observed in de novo acute myeloid leukemia is characterized by the absence of pre- leukemia, and association with abnormalities cytogenetic specific : the transfer sites AML with the band 11q23, and epipodophylotoxines to use and t (8, 21), T (15, 17) and inv (16 ) to combat money laundering , and use Antrasiklin . In combination , these anomalies classic This page has blamed himself and the same clinical diagnosis of de novo AML. The prognosis is more conservative in complex anomalies .

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