Monday, December 3, 2012

Other cytokines


 The first and second phase in progress to the therapeutic potential of TGF beta and IL-10, and two anti-inflammatory cytokines, and to consider at the moment for recombinant products. Since associated with the production of IL-12 with the progress of the disease and that may prevent by management that EAE anti-12-IL, these antibodies, in a clinical study evaluating the treatment of MS. Currently, it is still premature to take a decision on the therapeutic ability. You should know that many cytokines, and different functions, depending on the context, and more importantly, in the first place to work locally on the likely unintended consequences when administered into the general circulation.

Pentoxifylline is a phosphodiesterase inhibitor, which promotes the production of anti-inflammatory cytokines and prevent pro-inflammatory cytokines, while reducing the production of TNF-alpha. It has been shown to be effective in suppressing EAE. Are examined therapeutic ability in MS in a series of experimental studies. Its effects on various parameters of the immune system (CSF all of the blood) as well as magnetic resonance imaging and clinical, however, has been disappointing so far. According to a study, it was used for side effects., Associated with the early stages of antiretroviral therapy with interferon beta

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